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Start with dietary sources first and add supplements only to fill the gap

e.g., acrylamide) formed by high-temperature industrial frying, which has been suggested to contribute to neuroinflammation and neurotoxicity mediated through the generation of free radicals, mitochondrial dysfunction and activation of glial cells such as BV-2 microglial cells, primary astrocytes, and microglia, together inducing neuronal apoptosis (8, 4850)

Particularly those who spend hours in air-conditioned settings, whose muscular rigidity is weakened

Bm-TFF2, a trefoil factor protein with platelet activation activity from frog bombina maxima skin secretions

Gallagher et al., 2006)