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Sep 2013;74(9):902-17

and approved and licensed by the US Food and Drug Administration (FDA) in May 2006, [26] In 2011, the FDA approved the live vaccine for use in individuals 50 to 59 years of age

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It may help when neuropathy is worsened by B vitamin deficiency and is often used as an adjunct, but it is not a substitute for blood sugar control or dedicated neuropathic pain medications

Therefore, the downstream response blocked by MC4R deficiency could affect the anorexigenic effect of the GLP-1analog, but its effect has not been confirmed yet