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This observation is at first paradoxical, considering that NAC is a well-known antidote for glutathione-depleting toxicants such as paracetamol overdose and that NAC yields mercury conjugates [17]
Yes, says Dr Barnish who describes something called fluid overload. If it is not severe, typically this will resolve on its own over time, but can cause symptoms such as swollen fingers, bloating and fatigue, he says
HuangYKypridemosCLiuJLeeYPearson-StuttardJCollinsBet al
Bardoxolone methyl: drug development for diabetic kidney disease
Free Radic Biol Med 27:985991 Kraft AD, Johnson DA, Johnson JA (2004) Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
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