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It not only interacts with tight junction proteins in epithelial cells to maintain the integrity of the physical barrier but also regulates DCs, neutrophils, macrophages, and the differentiation of T lymphocyte subgroups, thereby inhibiting the release of proinflammatory cytokines and chemokines to achieve immune regulation (120)

ERK/MAPK signalling pathway and tumorigenesis

reported that cell proliferation was significantly inhibited after treating NSCLC cell lines with different concentrations of EGCG

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Melatonin gels of differing concentrations were then applied topically to the oral mucosa prior to radiation exposure