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Most patients experience side effects (nausea, appetite suppression, digestive changes) most prominently during the first 36 months, then adapt as their body adjusts to the medication

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Some people, especially those with a history of disordered eating, chronic stress, hormone imbalances, or certain medical conditions, may find that fasting worsens their symptoms or creates an unhealthy relationship with food

Aging Cell 20 , e13360 (2021)

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