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P., Jr (2018)

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[13] DSS Model Results : Weight loss significantly reduced at day 8 Myeloperoxidase activity (neutrophil marker) dropped 50% Prevented colon weight increase and length decrease IL-6 and IL-12 mRNA expression significantly reduced Histology showed less inflammation, reduced cell damage, fewer inflammatory cells in tissue layers TNBS Model Results (more acute inflammation): Weight loss reduced within 1-2 days post-TNBS Colonic MPO activity decreased 30% Prevented TNBS-induced colon shortening Broad cytokine suppression: IL-1, IL-6, TNF-, IFN- mRNA all reduced KPV didnt affect inflammatory markers in healthy mice

This approach makes theoretical sense

The protocol is built based on your clinical goals and the assessment at your first appointment, not based on what is most expensive