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Rapid titration may offer short-term benefits, but it increases the risk of side effects and treatment discontinuation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Guo J., Wang S., Xia H., Shi D., Chen Y., Zheng S., Chen Y., Gao H., Guo F., Ji Z., Huang C., Luo R., Zhang Y., Zuo J., Chen Y., Xu Y., Xia J., Zhu C., Xu X., Qiu Y., Sheng J., Xu K., Li L

Human and non-human trials have also noted occurrences of non-gastrointestinal side effects including allergic reactions, hypoglycemia, diabetic retinopathy complications, c-cell tumors, acute kidney injury and worsening of chronic renal failure

Medications that inhibit these enzymes (like certain blood pressure medications) may alter DSIP metabolism