doi: 10.4103/jisp.jisp_555_18
Studies in mice demonstrated that a short course of MOTS-c treatment completely reversed age-related insulin resistance in old muscles after one week of MOTS-c administration, older mices muscles responded to insulin as effectively as those of much younger mice
These effects were particularly pronounced when EAAT3 was co-overexpressed with xCT [46]
Unlike treatments designed specifically for weight management, BPC-157 does not seem to: Reduce appetite Increase feelings of fullness Trigger fat burning Significantly increase calorie expenditure Instead, any potential weight-related benefits are generally believed to occur indirectly through improvements in recovery, mobility, and overall physical function
Topical application through cream or serum can work for localized skin improvements, but absorption is limited, concentrations in commercial products are often insufficient, and youre not getting systemic effects that benefit hair follicles, internal wound healing, or broader tissue remodeling