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Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

Vitamin B12 deficiency in the elderly

Reticulocytosis (increased production of immature red blood cells) typically begins by day 3-4 of starting treatment, indicating active bone marrow recovery

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Response: We reiterate that our review of these codes and our rationale for finalizing the current values were discussed in the CY 2019 PFS final rule (83 FR 59517 through 59521) and the CY 2021 PFS final rule (85 FR 84602 through 84604)