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Hypoglycaemia can occur with GLP-1 agonists, especially if used alongside sulfonylureas or insulin.3 Diabetics on GLP-1 Agonists can also present with episodes of hyperglycaemia and DKA.3 In such cases, it is important to look beyond the acute management and consider whether problems with regular access to medication is a contributing factor

Later, Lotte Knudsen and her team created analogues of human GLP1

This type of injury requires close monitoring and sometimes immediate intervention to prevent further damage

Retatrutide targets three (GLP-1, GIP, and Glucagon), which researchers believe may lead to more significant metabolic improvements