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These effects are blunted by vagotomy or pharmacological GLP-1R blockade, and by genetic inactivation of GLP-1R signaling in whole body or selectively in vagal afferents

J Cell Physiol 143: 165171

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Just as GLP-1 drugs have been transformative in human weight management, they hold promise for our pets too

It also summarizes recent advances in drug discovery, including natural compounds, synthetic activators, and NAD + precursors, and evaluates their translational potential for MASLD therapy