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Activation of the glucagon receptor increases energy expenditure in the liver and adipose tissue, promoting fat breakdown and enabling the body to burn more calories

Clinicians might consider preferring GLP-1 receptor agonists over other diabetes treatments, such as insulin, for patients at high risk of obesity-associated cancers. Wang and colleagues conducted a retrospective cohort study of deidentified electronic health records on the TriNetX platform

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The authors also note that the patient did not initially disclose his alcohol use because of guilt and stigma, highlighting the need for stronger AUD screening and diagnostic efforts within family medicine clinics