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Moreover, our analysis of seven patients from the combined therapy group suggests that GLP-1 agonists allow for a reduction in acetazolamide dosage in the treatment of IIH without changing the clinical outcome

STEP 5 Two-Year Safety Results In the STEP 5 trial involving 304 participants (152 receiving semaglutide, 152 receiving placebo), gastrointestinal adverse events occurred in 82.2% of the semaglutide group versus 53.9% of the placebo group over the two-year period