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It can also activate transient receptor potential vanilloid 1 (TRPV1) channels, altering visceral pain thresholds, and participate in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis and stress responses

Luo G, et al

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Cells recover faster from oxidative hits, maintain function under metabolic stress, and show lower rates of apoptosis in reproductive tissues

En el campo oncolgico experimental, lneas celulares que sobreexpresan NNMT han servido para explorar la dependencia tumoral de esta enzima y el efecto de su inhibicin sobre proliferacin y metabolismo