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ITS serves as a foundational cell culture media supplement for epithelial, mesenchymal, and progenitor cell systems where serum is contraindicated [2]

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In contrast to our results, the authors demonstrated an increase in ECAR within the first hour following in vitro LPS addition and interpreted this as indicative of a switch from oxidative phosphorylation to increased glycolysis as part of the M1 macrophage response following LPS stimulation (51)

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