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Others work more selectively on the intestines and have less risks

Lose weight or address body composition changes: Ask your clinician about GLP-1s (like semaglutide or tirzepatide), other meds like Contrave or metformin, supplements like berberine, and other lifestyle strategies

Vitamin B12 injections are the most common way to prevent or treat a deficiency

May Reduce Inflammation Preliminary studies suggest that NNMT inhibition may lower systemic inflammation markers , helping reduce the oxidative stress burden that accelerates aging and disease progression

Potential Side Effects Though generally safe, B12 injections can have potential side effects