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In line with clinical data, GLP-1R agonism may also directly influence food preference through modulation of taste receptor expression
As per the agreement, Merck will pay $112 million upfront, while pledging up to $1.9 billion in development, regulatory and commercial milestones
Roche for example paid $2.7bn to acquire privately held Carmot Therapeutics while AstraZeneca in-licensed an oral drug from Chinas Eccogene for $185m upfront (and $1.8bn of potential milestones)
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