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5,6 Such neurotoxic aggregates appear critical in the disease progression of each of these disorders 36 and can occur across them

Across technical and preclinical contexts, these peptides are referenced strictly for educational and research purposes, with emphasis on analytical handling, standardized protocols, and pathway-focused investigation under appropriately controlled laboratory conditions

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This publication provides validated evidence that neurofilament proteins can serve as biomarkers to subclassify disease severity in patients with ALS and also as markers of phenoconversion in pre-symptomatic carriers of pathogenic mutations