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Although less common, some people experience more severe adverse reactions to topiramate, such as: Kidney stones , hard deposits of minerals in the kidneys that can cause back or flank (side) pain, nausea, vomiting, and bloody, cloudy, or smelly urine Metabolic acidosis, a condition in which too much acid is in the bloodstream, leading to irregular heartbeat, fatigue, and confusion

GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the dual agonist tirzepatide carry the evidence: STEP for semaglutide (NEJM 2021), SURMOUNT for tirzepatide (NEJM 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM 2024)

Retatrutide, Eli Lillys next-generation triple-action therapy, has once again demonstrated meaningful efficacy in clinical trials

L-carnitine capsules help increase energy levels, support muscle recovery, and improve overall physical fitness