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GHK-Cu plays an important role in tissue regeneration, wound healing, and skin remodeling through multiple mechanisms: it promotes the recruitment and activation of repair cells, enhances the synthesis of extracellular matrix components (including collagen, elastin, and glycosaminoglycans), modulates extracellular matrix turnover by increasing both metalloproteinases and their inhibitors, and exhibits powerful anti-inflammatory and antioxidant effects

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Its given by subcutaneous injection, usually once or twice a day

Mediation analysis of the contribution of weight loss to MASH improvement To investigate whether semaglutide improved liver histology through weight loss or via mechanisms separate from weight, mediation analyses using natural effects models were performed