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Although gastrointestinal side effects are well documented, less is known about how users assess the trade-off between perceived benefits and adverse effects, or how these assessments influence treatment discontinuation

Analyses were anchored in ventricular CSF to capture central nervous system biology, with additional profiling of lumbar CSF and plasma to evaluate how these signals extend across biofluids

Several competitors are pursuing similar or alternative approaches, and the competitive landscape could influence pricing, availability, and insurance coverage

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In severe cases, skin and underlying tissue can suffer necrosis (tissue death), requiring antibiotics or surgery to treat