In a study conducted by Bhat et al., N-arylphthalimides derived from thalidomide, modified by the addition of hydrophobic groups, were evaluated for their anti-inflammatory effects, with compound 33 emerging as a potential anti-inflammatory agent
Furthermore, both IGF-I and the IGF-IR are expressed in the developing glomerulus and patterns of expression are disrupted in animal models and in human examples of renal disease[140]
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