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Lyophilized research products should be stored in a cool, dry environment prior to preparation to help maintain long-term stability and purity

If the FDA ultimately follows the panel's recommendation, compounding pharmacy versions would at least be produced under state pharmacy board oversight and require a physician's prescription

Because human clinical data is absent, the full risk profile for cardiovascular use is unknown

Are there clinical features of liver disease, myeloproliferative disorder (e.g., blood film changes of unexplained cytopenia, thrombocytosis, or leukocytosis), or another cancer (e.g., cachexia, constitutional symptoms fever, weight loss, night sweats)

Too much Vitamin B12 can also mess with chemotherapy