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The OGTT and the Child-Pugh score were independent predictors of death, suggesting that there might be a synergistic effect between conditions.17 DM might induce liver damage by promoting inflammation and fibrosis through an increase in mitochondrial oxidative stress by the action of leptin, adiponectin, interleukin-6 and TNF-, which are produced in chronically inflamed adipose tissue (adipositis).19,20 The production of these chemical mediators is stimulated by insulin resistance (RI)

For individuals with type 2 diabetes, this means demonstrating stable treatment and absence of significant diabetes-related complications

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Evidence supporting postbiotics in obesity management is derived predominantly from mechanistic and preclinical studies, with an emerging but heterogeneous body of human trial evidence indicating modest and variable effects on anthropometric outcomes

Integrated 24 h GH concentration is significantly greater in women than in men and greater in the young than in the old adults