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"Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial"

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It also increases plasma BDNF levels, providing a measurable biomarker of its neurotrophic activity

Additionally, the exposed group demonstrated significantly higher PLA 2 and SMase enzyme activity, with their median values being 518 and 706 AFU/mg, compared to 267 and 444 AFU/mg in the unexposed workers

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