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Other possible causes of a vitamin B12 deficiency pernicious anemia prolonged use of certain medications, such as metformin following a strict vegan or vegetarian diet certain infections, such as with the tapeworm Diphyllobothrium latum celiac disease older age high intake of alcohol Other nutritional supplements may also benefit someone with Crohns disease

257 In addition, the chance of pregnancy is lower if damage to motility or morphology affects a large percentage of sperm, abnormalities in sperm function are identified, or the female partner is over 40 years old

Second, the increase in synaptic norepinephrine directly stimulates the sympathetic nervous system