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The following sections review the pharmacology and clinical characteristics of currently available GLP-1 RAs that should be considered when applying the clinical recommendations discussed above to individual patients with T2D

The first of these drugs, cimetidine, was developed by James Black (figure 27), a Scottish physician and pharmacologist with a long-standing interest in the gut and the challenge of treating gastric and duodenal ulcers

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Habegger, University of Alabama at Birmingham, United States Reviewed by Thomas Alexander Lutz, University of Zurich, Switzerland Jarrad Scarlett, University of Washington, United States Updates Copyright 2025 Douros, Flak and Knerr