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These challenges highlight a need for new research aimed at better understanding TBI pathogenesis and identifying specific biomarkers corresponding to underlying cellular, structural and secretomic changes that can improve clinical decision making

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For optimal results, injections should be used alongside a balanced diet, regular exercise (both cardio and strength training), and adequate hydration

Since in some of the studies analysed type 2 diabetic patients were treated with metformin, which has been shown to enhance GLP-1 responses [51], any potential difference in GLP-1 secretory responses between type 2 diabetic patients and healthy participants may have been modified by this mechanism