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Dont Rush Your Dose Increases Many patients feel the urge to increase their dose quickly, but sticking at a lower dose for longer (especially if its working) can meaningfully reduce your monthly spend without affecting your results

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Adaptation of N -methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression

Multiple reports have linked IBS pathogenesis with dysbiosis, a condition that refers to decrease/loss of microbial diversity and richness, owing to the changes from commensal bacteria to pathogens in the human gut ( Lactobacilli and Bifidobacteria are heavily compromised in IBS patients (Tap et al., 2017)