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Uzoigwe C, Liang Y, Whitmire S, Paprocki Y
DFO did not dramatically decrease total brain iron content, but it appeared to redistribute iron from vulnerable regions of disease pathology (Guo et al., 2015), suggesting that DFO can possibly stabilize iron in forms that are less neurotoxic
Always consult your healthcare provider before starting any treatment
Cell culture Bone marrow-derived macrophages (BMDMs) were harvested from the femur and tibia of C57BL/6J mice and cultured in Dulbeccos modified Eagles medium (DMEM) containing 10% fetal bovine serum (FBS, Gibco, Carlsbad, CA, USA) and 10% L929 cell-conditioned medium, and maintained in a humidified incubator with 5% CO 2 at 37 C for 7 days [36]