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118 Autoradiographic and radioligand binding experiments have localized AT 4 binding sites on microvilli and cell bodies of rat proximal convoluted and straight tubules, 17 cultured rat mesangial cells, 111 cultured opossum proximal tubule cells, 119 apical and basolateral membranes of rabbit cortical tubules, 119 cultured rabbit 120 and human collecting duct cells 121 and cultured human proximal tubule epithelial cells

The outer layer starts to get weaker and bulges into the spinal canal

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May influence gene expression related to repair processes