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Notably, brain tumourigenesis may cause dysbiosis of the gut microbiota, as evidenced in mice model studies discussed above

A single temperature excursion or improper seal can turn pharmaceutical-grade BAC water into a bacterial breeding ground within 72 hours

Walton et al., 2017)

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Protein aggregation While the greater risk of cognitive decline and disability associated with LLD may be associated with neurodegeneration, including abnormal protein deposition (A, Tau and -synuclein), neuroinflammation and reduced synaptic integrity, the available evidence is controversial