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Briefly, 100 l of reaction mixture in 50 mM sodium phosphate buffer (pH 8.0) contained 10 mM MgCl 2 , 10 mM ATP, 5 mM agmatine, 4 M Cp1D or Cp2D, various concentrations of (2 S ,3 S )- t -ES-Ile or (2 R ,3 R )- t -ES-Ile

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The results demonstrated that BPC 157 caused a significant reduction in all of the necrosis markers commonly measured in routine practice (i.e., CK, CK-MB, LDH, and cTnT) and attenuated gross (no visible infarcted area) and histological damage, including ECG (no ST-T ischemic changes) and echocardiography (preservation of systolic left ventricular function) damage induced by isoprenaline

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