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Sodium-glucose cotransporter-2 inhibitor (SGLT2i) plus glucagon-like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase-4 inhibitor combination in treating obese mice metabolic dysfunction-associated steatotic liver disease (MASLD)

Kotler et al

First, clinical validation remains inadequate: although preclinical data highlight the promise of multimodal therapies (e.g., co-delivering urate-lowering agents and anti-inflammatory drugs), robust clinical evidence is lacking