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All methods were carried out in accordance with concerned laws and Biosafety Manual in RIKEN

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An early RCT in 44 patients with obesity and subclinical binge eating showed that liraglutide was better than diet and exercise alone in reducing binge-eating scores at 12 weeks 220 , but a later investigation of 27 adults with BED comparing liraglutide against placebo did not find any differences in the number of binging episodes over 17 weeks 218