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Any medication adjustments, including changes to the tirzepatide dose or titration schedule, should be made under healthcare provider guidance based on overall tolerability and treatment goals

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Watch for: Significantly decreased urine output Dark-colored urine that does not improve with hydration Swelling in the ankles or feet Persistent fatigue with decreased urination Semaglutide side effects compared to other GLP-1 medications If you are considering semaglutide versus tirzepatide or evaluating other options, understanding how side effect profiles compare helps inform decision-making

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Incretin based drugs and risk of cholangiocarcinoma among patients with type 2 diabetes: population based cohort study