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Automatic data collection was performed on a Titan Krios equipped with a Gatan K2 Summit direct electron detector in the Center of Cryo-Electron Microscopy, Zhejiang University (Hangzhou, China)

Moreover, POC ultrasound was not used prior to endoscopy to determine RGC in any of the case reports or studies included in our manuscript

Heart failure was obtained from Heart Failure Molecular Epidemiology for Therapeutic Targets (HERMES) consortium, with 47,309 cases and 930,014 controls [27]