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The potential beneficial substances from plants, known as phytochemicals, are still being explored

SIBO bacteria can cause histamine intolerance indirectly The first consideration is small intestine bacterial overgrowth (SIBO)

Kobayashi T, Matsumine H, Matuda S, Mizuno Y

N-Acetyl-L-Cysteine (NAC) is a synthetic derivative of the naturally occurring amino acid L-cysteine, featuring an attached acetyl group that significantly enhances its chemical stability, cellular absorption, and overall bioavailability

Further applying spatial transcriptomics, combined with immunostaining, we found that aCD3 preserved beta cell identity, whereas GLP1-E2 attenuated ER stress, inflammatory signalling and antigen presentation, consistent with reduced beta cell immunogenicity