While our findings indicate that NF-B can specifically bind to EAAT3 promoter regions in certain cell types, multiple pathways and factors are known to regulate EAAT3, including the NRF2-ARE pathway [51], the RFX1 transcription factor [52], NFAT5/TonEBP [53], and ATRA [54]
If AEs were manageable, dose escalation was continued as per the given schedule
Tell your healthcare provider right away if you get symptoms which may include: pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools
Its important to ask your care provider or pharmacist any specific questions you may have
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