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Studies have shown that patients using GLP-1 receptor agonists, alongside lifestyle modifications, can achieve an average weight reduction of 1015% of their body weight over time with improvements in blood sugar control, blood pressure, and cholesterol levels

The prescription of GLP-1 RAs in persons with SMI-SUD needs to be informed by the reported safety and tolerability profiles of these agents, with some aspects of relevance to persons with SMI-SUD (Table 1)

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