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For instance, protein disulfide isomerase (PDI) deficiency, which induces misfolding stress in the ER, has been linked to disruptions in focal adhesions and cytoskeleton organization, particularly through the downregulation of MSN and CNN3 [70] both of which were observed to be downregulated in our proteomic analysis

Collectively, the non-canonical peptide sequences, i.e., not templated in the genome, resulting from these processes will be referred to as alternative antigens (also termed neo-antigens in the literature)

7-Keto-cholesterol and cholestan-3beta, 5alpha, 6beta-triol induce eryptosis through distinct pathways leading to NADPH oxidase and nitric oxide synthase activation

PubMed record Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P

L-Methionine can also be converted into SAMe (S-Adenosyl Methionine), a compound that supports healthy joints