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SSRIs such as fluoxetine may occasionally be considered by specialists to address comorbid depression or anxiety in people with BED, but this is also off-label and should only be initiated by a qualified clinician

Empagliflozin is also PBS listed for HFrEF, independent of diabetes status, but is not currently TGA approved for CKD

Although cytokines are necessary for fighting infections, high levels of cytokines lead to chronic inflammation and resultant tissue injury

It stimulates insulin secretion, suppresses glucagon release, slows gastric emptying, and acts on brain receptors to reduce appetite

Sehgal is very professional yet approachable