doi: 10.3389/fphar.2025.1561351 Received 15 January 2025 Accepted 09 May 2025 Published 26 May 2025 Volume 16 - 2025 Edited by Ruyu Yao, Chinese Academy of Sciences (CAS), China Reviewed by Sharifah Alawieyah Syed Mortadza, Putra Malaysia University, Malaysia Alisson Mcario de Oliveira, State University of Paraba, Brazil Updates Copyright 2025 Zhi, He, Xue, Zhao, Gong, Guo, Luo, Tian and Dong
Key findings: Prescribing trends Using a subset of real-world electronic health record (EHR) data from Truveta, Truveta Research identified people who were prescribed a GLP-1 RA between January 01, 2018 and March 31, 2024
February 2003
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Our data showed that pretreatment with a GLP-1R agonist alleviated the expression of ER stress-related proteins, such as PDI, GRP78, CHOP, and caspase-12, which increase in response to ER stress and are considered to be mediators of apoptotic pathways 45,46 , which were partial reversed by LY294002
