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WHAT RESEARCHERS LOOK AT Mechanism: triple receptor agonism at GLP-1, GIP, and glucagon receptors

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Prescription fills for patients without diabetes (off-label use) tripled between 2022 and 2023

Neurohormonal Support & Mood Stabilization: Tesofensine works synergistically with methylated B6, B12, Folate, and Alpha-GPC to support dopaminergic and serotonergic pathways, enhancing mental clarity, mood balance, and stress resilience

Our findings, derived from administrative data, cannot be transferred directly into the clinical practice, but they do provide a strong rationale for further investigation on the potential clinical benefit of these agents also in the in-hospital treatment of AMI