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1 Although toxic ingestions causing hepatic failure are usually in excess of 150 mg/kg, an increasing number of reports has arisen to suggest that lower doses of APAP may confer acute liver injury and liver failure

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Limitations: It is uncertain that the members of the control group were totally disease-free

A pump is programmed based on the number and size of infusions being administered to ensure all medicine is fully administered without allowing the access line to run dry