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This is largely due to its selective action, meaning it primarily stimulates the release of growth hormone without significantly impacting other hormones like cortisol or prolactin

Excess fumarate, resulting from impaired TCA function, accumulates in the cytoplasm and reacts with thiol groups in crucial cellular proteins, leading to succination and inactivation [81, 82]

It was concluded that small changes in the GSH/GSSG ratio is amplified to large effects on redox potential through the oxidation/reduction of cysteine residues within proteins, rather than changes in the GSH/GSSG ratio directly affecting the cellular redox potential [11]

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Food may provide a buffering effect that helps reduce gastrointestinal irritation