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While major contraceptive failures are uncommon, the risk exists, particularly if you take a lower-dose birth control formulation or have naturally slower digestion

GLP-1 Receptor Agonists: An Updated Review of Head-to-Head Clinical Studies. Therapeutic Advances in Endocrinology and Metabolism, SAGE Publications, 9 Mar

Both of these categories of supplements are very opportunistically taking advantage of the lax laws around supplements to jump in and try to profit from a group of medications that are truly effective, says Pieter Cohen, an associate professor of medicine at Harvard Medical School who studies supplements

Osteoporosis The potential impact of GLP-1RAs on bone metabolism has been examined in three recent reviews [104,105,106]

PMID 32848151