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We already know that GLP-1 receptors are present in the brain

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Es importante sealar que s existe evidencia de taquifilaxia (reduccin del efecto con el tiempo) especficamente para el efecto de retraso del vaciamiento gstrico con el uso crnico de agonistas de GLP-1, aunque los efectos metablicos centrales y de control glucmico tienden a mantenerse