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68 HP 125 FRAG 176-191 HGH C-Terminal Fragment Lipolytic Only ALIASES Frag 176-191, HGH Fragment 176-191, AOD-9604 parent fragment, lipolytic HGH C-terminus CLASS Synthetic peptide HGH C-terminal lipolytic fragment FORMULA C78H125N23O23S2 SEQUENCE Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (residues 176-191 of human GH) HALF-LIFE ~30 minutes (rapid plasma clearance) ROUTES Subcutaneous (research) MECHANISM OF ACTION 16-amino-acid C-terminal fragment of human growth hormone (residues 176-191), also known as AOD-9604 in its modified form

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How peripherally administered GLP-1 induces satiety mechanistically is unclear, but it is postulated that signals being generated by the binding of GLP-1 to its receptor on neurons in the GIT, hepatoportal bed and CNS mediate this effect

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