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Materials and methods Experimental design and induction of the PCOS rat model The ethics committee of Shiraz University of Medical Sciences approved the study protocol (IR.SUMS.AEC.1403.010)

GLP-1 therapy accelerates part of this process

In other words, it helps keep the drawbridges of the gut raised, preventing substances such as bacteria, lipopolysaccharides (endotoxins), and other inflammatory compounds from entering the body

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The small sample size of the GLP-1RA, however, limits generalizability, and baseline BMI differences may have influenced the observed outcomes